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Article data
Lippi (2020)
Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis
https://doi.org/10.1016/j.cca.2020.03.022
https://www.sciencedirect.com/science/article/pii/S0009898120301248

Results
Complications
Thrombocytopenia (Present vs. Not present)
COVID-19 (severe/critical)
Odds ratio: 5.130 (1.810-14.580) Univariate analysis

Study characteristics

China and Singapore

Meta-analysis

Published studies

1289

all documents reporting information on platelet count (either the value or the rate of thrombocytopenia) in COVID-19 patients with a clinically validated definition of severe disease

Study 1- median age is 47, 41.9% females Study 2-median age is 49, 28% females Study 3-mean age is 54, 33% females Sutdy 4-median age 56, 38% females

Not stated

0


Results

COVID-19 (severe/critical)

246

Severe COVID-19 disease

Complications

Thrombocytopenia

Not present

Present

Odds ratio

5.130 (1.810-14.580)

No

Yes

No

Not applicable


Other information

Did not specify the timing of thrombocytopenia assessment. Only 4 studies reporting the rate of thrombocytopenia were included in the analysis for the association between thrombocytopenia and severe disease. Number of cases and total number of patients not stated

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