Jin (2020)
Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms
32213556
https://www.ncbi.nlm.nih.gov/pubmed/32213556
Patient characteristics
Symptoms (From infected area vs. Not applicable)
COVID-19 (severe/critical)
Odds ratio: 0.090 (0.020-0.540) Adjusted model

China

Retrospective observational study

Medical records

74

N=74 confirmed COVID-19 cases with GI symptom

Among enrolled 651 patients, 74 (11.4%) presented with at least one GI symptom (nausea, vomiting or diarrhoea), average age of 46.14 years, 4-day incubation period and 10.8% had pre-existing liver disease. Patients in the Zhejiang province from 17 January 2020 to 8 February 2020 s in the Zhejiang province to determine epidemiological, clinical and virological characteristics.

Total

0


COVID-19 (severe/critical)

17

The severe type was diagnosed according to dyspnoea (respiratory rate (RR) >=30 times/min), resting finger oxygen saturation <=93%, artery PaO2/FiO2<=300mm Hg (1 mm Hg=0.133kPa). The critical type is defined as respiratory failure with shock and multiorgan failure requiring mechanical ventilation and intensive care unit (ICU) admission. The definition of liver damage was alanine aminotransferase (ALT) >50U/L or aspartate aminotransferase (AST) >40U/L.


Patient characteristics

Symptoms

none

Not applicable

From infected area


Odds ratio

0.090 (0.020-0.540)

No

Yes

Yes

Sputum production, of patients from infected areas, increased LDH, increased glucose levels


none

Good

Yes