Wang (2020)
Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up
https://doi.org/10.1016/j.jinf.2020.03.019
https://www.ncbi.nlm.nih.gov/pubmed/32240670
Complications
Cardiac insufficiency (Present vs. Not present)
COVID-19 (death)
Hazard ratio: 1.110 (0.590-2.060) Adjusted model

China

Retrospective study

Medical records

339

All confirmed cases of COVID-19 over 60 years old admitted from Jan 1 to Feb 6 at isolation ward of Renmin Hospital of Wuhan University in Wuhan, China which is a designated hospital capable of receiving severe COVID-19 patients.

Of 339 patients identified, the mean age was 71 years, and 173 were female (51%). 60.7% of the patients had comorbidities, while 23.9% had two or more comorbidities.

Median

28 Day


COVID-19 (death)

65

Elderly patients with COVID-19


Complications

Cardiac insufficiency

Cardiac insufficiency was defined when the serum level of NT-pro BNP exceeded the normal range and the presence of associated symptoms, such as dyspnea, orthopnea and edema of lower extremity.

Not present

40

281

Present

25

58


Hazard ratio

1.110 (0.590-2.060)

No

No

Yes

Age, acute cardiac injury, arrhythmia, AKI, ARDS, cardiac insufficiency, bacterial infection


Complications including acute cardiac injury, arrhythmia, acute kidney injury (AKI), ARDS, cardiac insufficiency and bacterial infection were all predictors of death.

Average

Yes