Zheng (2020)
Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease
https://doi.org/10.1016/j.metabol.2020.154244
https://www.ncbi.nlm.nih.gov/pubmed/32320741
Comorbidities
Overweight/obesity (Overweight (25-29kg/m2) vs. Normal (<25 kg/m2))
COVID-19 (severe/critical)
Odds ratio: 6.320 (1.160-34.540) Adjusted model

China

Retrospective observational study

Medical records

66

Consecutively enrolled patients with laboratory-confirmed COVID-19 with metabolic associated fatty liver disease

aged between 18 and 75 years from three hospitals in Wenzhou, China (the First Affiliated Hospital of Wenzhou Medical University, Wenzhou Central Hospital, and Ruian People's Hospital) between January 1, 2020 and February 29, 2020. COVID-19 was diagnosed as a positive result by high-throughput sequencing or real-time reverse transcriptase-polymerase chain reaction assay of oropharyngeal swab specimens.

0


COVID-19 (severe/critical)

19

COVID-19 severity was assessed during hospitalization and classified as severe and non-severe based on the management guideline.


Comorbidities

Overweight/obesity

Obesity-overweight above 25kb/m2

Normal (<25 kg/m2)

Overweight (25-29kg/m2)


Odds ratio

6.320 (1.160-34.540)

No

Yes

Yes

adjusted for age, sex, smoking, type 2 diabetes, hypertension, and dyslipidemia.


none

Average

No