Loffredo (2020)
Conjunctivitis and COVID-19: a meta-analysis.
https://doi.org/10.1002/jmv.25938
https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmv.25938
Symptoms
Conjunctivitis (Present vs. Not present)
COVID-19 (severe/fatal)
Odds ratio: 3.390 (1.125-10.212) Univariate analysis

China

Meta-analysis

Registry

1167

Meta-analysis with studies that included patients with severe vs non-severe form of COVID-19 infection. (3 studies: Xia, Guan, Wu)

The age of the patients enrolled ranged from a median of 47 to 68 years old and the male sex was prevalent in all the studies. We included studies in patients with COVID-19 that assessed the severe (as severe pneumonia, mortality, ARDS, use of mechanical ventilation or intensive care units recovery) and non-severe forms of the disease and reported the incidence of conjunctivitis

0


COVID-19 (severe/fatal)

197

severe pneumonia, mortality, ARDS, use of mechanical ventilation or intensive care units recovery


Symptoms

Conjunctivitis

Patients with severe COVID-19 infection had, at admission to the hospital, increased incidence of conjunctivitis (O.R.:3.4; 95% C.I.:1.1-10.2; p=0.030).

Not present

191

1154

Present

6

13


Odds ratio

3.390 (1.125-10.212)

No

Yes

No

pooled odds ratio


None

Good

Yes