Zhang (2020)
Clinical characteristics and chest CT imaging features of critically ill COVID-19 patients
https://doi.org/10.1007/s00330-020-06955-x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260469/
Symptoms
Sputum production (Present vs. Not present)
COVID-19 (death)
Odds ratio: 0.786 (0.202-3.060) Univariate analysis

China

Retrospective cohort study

Medical records

60

We retrospectively reviewed the medical records of 60 critically ill COVID-19 pneumonia patients who were admitted to a hospital in Wuhan, Hubei Province, and another in Huaihua, Hunan Province, between 9 January 2020 and 19 February 2020.

Of the 60 patients, 43 were males (71.7%), and their mean age was 64.4 ± 11.0 years. Patients who were deceased were older than those who recovered (mean age, 70.6 vs. 62.6 years, p =0.044). The mean time between symptom onset to admission was 8.9 ± 5.0 days. Of the 60 patients, 43 were males (71.7%), and their mean age was 64.4±11.0 years. Patients who were deceased were older than those who recovered (mean age, 70.6 vs. 62.6 years, p=0.044). The mean time between symptom onset to admission was 8.9±5.0 days. Ten patients died in this study cohort during hospitalization for treatment, establishing the mortality of critically ill COVID-19 pneumonia patients to be 17%. The condition of the remaining 50 patients improved, and they were discharged from the hospitals. Their clinical and medical records were analyzed, and the chest CT images were assessed to determine the involvement of lobes and the distribution of lesions in the lungs between the patients who recovered from the illness and those who died.

Total

42 Day


COVID-19 (death)

10

10 (17%) patients died. According to the criteria for clinical severity of confirmed COVID-19 pneumonia, the patients of severe and critical type were defined as being critically ill.


Symptoms

Sputum production

Mucus, thicker than normal due to illness.

Not present

Present


Odds ratio

0.786 (0.202-3.060)

No

No

No

Continuous variables were expressed as mean ± standard deviation (SD). The odds ratio to determine their association with clinical outcomes in terms of deceased or recovered status.


none

Average

Yes