China
Prospective cohort study
Medical records
273
273 diagnosed COVID-19 patients with mild category in Shanghai Public Health Clinical Center were included in this analysis.
The average age of 273 COVID-19 patients enrolled with imaging progression were older than those without imaging progression (p = 0.006). The optimal cutoff of age for predicting imaging progression on chest CT was 51 years.
Total
7 Day
COVID-19 (severe/critical)
71
71 COVID-19 patients suffered from imaging progression on chest CT at first week after admission, and the other 202 patients were imaging progression-free on chest CT.
Laboratory Findings
Homocysteine
Homocysteine, umol/L (>15.4 vs < 15.4) Homocysteine is a type of amino acid, a chemical your body uses to make proteins. Normally, vitamin B12, vitamin B6, and folic acid break down homocysteine
Normal
Abnormal
Risk ratio
3.170 (1.010-9.960)
No
Yes
Age, gamma globulin therapy, thymosin therapy, Monocyte-lymphocyte ratio (MLR), serum cystatin C, homocysteine, estimated glomerular filtration rate (eGFR) and period from onset to admission.
Age, MLR, homocysteine and period from onset to admission could predict imaging progression on chest CT from COVID-19
Good