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Article data
Xu (2020)
Risk factors for severe corona virus disease 2019 (COVID-19) patients : a systematic review and meta analysis
https://doi.org/10.1101/2020.03.30.20047415
https://www.medrxiv.org/content/10.1101/2020.03.30.20047415v1

Results
Patient characteristics
Age (1 year increase vs. Not applicable)
COVID-19 (severe/critical)
Weighted Mean Difference: 11.890 (8.630-15.140) Adjusted model

Study characteristics

China

Systematic reviwe and meta analysis

Medical records

4062

20 articles on risk factors (N=4062 participants) were included

All articles were observational studies. All the subjects are from China, including more than 30 provinces and cities. The study period spans from 11 December 2019 to 23 February 2020. About the comparison of mild and severe patients, 15 studies described patient characteristics, 15 studies described comorbidities, 8 studies described vital signs, 17 studies compared symptoms and 19 studies described laboratory findings.

0


Results

COVID-19 (severe/critical)

681

Definition of severe COVID-19[8]: Severe COVID-19 was designated when the patients had one of the following criteria:1) Respiratory distress with respiratory frequency?30/min; 2) Pulse Oximeter Oxygen Saturation?93% at rest; 3) Oxygenation index (artery partial pressure of oxygen/inspired oxygen fraction, PaO2/FiO2)?300 mmHg (1 mmHg=0.133 kPa). At high altitudes (above 1000 meters), PaO2 / FiO2 should be corrected according to the following criteria: PaO2 / FiO2 [Atmospheric Pressure (mmHg) / 760]. Pulmonary imaging showed that the lesions progressed more than 50% within 24-48 hours should be managed according to Critically ill patients.

Patient characteristics

Age

none

Not applicable

1 year increase

0

0

Weighted Mean Difference

11.890 (8.630-15.140)

No

Yes

Yes

random-effects model (I2=54.4%)


Other information

Number of cases and patients in reference and comparison are not reported.

Average

Yes

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