China
Retrospective cohort study
Medical records
449
Consecutive patients with severe COVID-19
181 females and 268 males. The mean age at disease onset was 65.1 years
Total
28 Day
COVID-19 (death)
134
Died within 28 days
Treatment
Treatment for COVID-19
none
Not received
104
350
Treated with heparin
30
99
Odds ratio
1.650 (0.930-2.920)
No
Yes
risk was adjusted for age, sex ratio, underlying disease, prothrombin time, platelet count and D-dimer
None
Good