Tang (2020)
Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy
https://doi.org/10.1111/JTH.14817
https://onlinelibrary.wiley.com/doi/10.1111/jth.14817
Treatment
Treatment for COVID-19 (Treated with heparin vs. Not received)
COVID-19 (death)
Odds ratio: 1.650 (0.930-2.920) Adjusted model. Calculated odds ratio based on data reported in the article.

China

Retrospective cohort study

Medical records

449

Consecutive patients with severe COVID-19

181 females and 268 males. The mean age at disease onset was 65.1 years

Total

28 Day


COVID-19 (death)

134

Died within 28 days


Treatment

Treatment for COVID-19

none

Not received

104

350

Treated with heparin

30

99


Odds ratio

1.650 (0.930-2.920)

No

No

Yes

risk was adjusted for age, sex ratio, underlying disease, prothrombin time, platelet count and D-dimer


None

Good

Yes