Deng (2020)
Case fatality risk of novel coronavirus diseases 2019 in China
https://doi.org/10.1101/2020.03.04.20031005
https://www.medrxiv.org/content/10.1101/2020.03.04.20031005v1.full.pdf
Status
Time from symptom onset to hospital admission (>3 days vs. <=3 days)
COVID-19 (death)
Odds ratio: 0.650 (0.200-2.110) Adjusted model

China

Prospective observational study

Medical records

9651

Laboratory-confirmed COVID-19 cases from publicly available official sources from December 29, 2019 to February 23, 2020.

The median age of the cases outside Hubei was 45 years (range, four days-97 years), and 51% (4,956/9,651) were male. Those who died were significantly older than discharged cases (median age: 77 vs 39 years, p<0.001). 77% (48/62) of deaths occurred in the older adults aged 65 years or above, and 58% (36/62) were male. Multivariate logistic analysis revealed that increasing age, being male, and living in less developed economic regions (e.g. Central region or West and Northeast region) were risk factors for mortality.

Total

2 Month


COVID-19 (death)

97

Risk factors associated with fatal outcome among COVID-19 patients. cases who may had outcomes (i.e., death/discharge/corresponding dates)


Status

Time from symptom onset to hospital admission

Estimated key time-to-event distributions including symptom onset to first healthcare consultation, hospital admission, laboratory diagnosis, and death or discharge, and from hospital admission to death or discharge

<=3 days

>3 days


Odds ratio

0.650 (0.200-2.110)

No

No

Yes

age, sex, economic region, time interval from symptom onset to first medical consultation, first hospital admission, and laboratory diagnosis


none

Average

Yes