Tang (2020)
Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy
https://doi.org/10.1111/JTH.14817
https://onlinelibrary.wiley.com/doi/10.1111/jth.14817
Treatment
Treatment for COVID-19 (Treated with heparin (patients with D-dimer >6 ULN) vs. Not received)
COVID-19 (death)
Odds ratio: 0.440 (0.230-0.870) Univariate analysis

China

Retrospective cohort study

Medical records

449

Consecutive patients with severe COVID-19

181 females and 268 males. The mean age at disease onset was 65.1 years

Total

28 Day


COVID-19 (death)

134

Died within 28 days


Treatment

Treatment for COVID-19

none

Not received

Treated with heparin (patients with D-dimer >6 ULN)


Odds ratio

0.440 (0.230-0.870)

Yes

No

No

Not applicable


ULN= upper limit of normal Stratified analysis was performed. Only patients with D-dimer >6 ULN were included (n=161) Number of cases and total number of patients in the reference/comparison category not available

Good

Yes