View Risk


Article data
Cummings (2020)
Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study
https://doi.org/10.1016/S0140-6736(20)31189-2
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31189-2/fulltext

Results
Laboratory Findings
IL-6 (1 unit increase vs. Not applicable)
COVID-19 (death)
Hazard ratio: 1.110 (1.020-1.200) Adjusted model

Study characteristics

United States of America

Prospective cohort study

Medical records

1150

Prospectively identified adult patients (aged>=18 years) admitted to two NewYork-Presbyterian hospitals from March 2 to April 1, 2020, who were diagnosed with laboratory confirmed COVID-19 and were critically ill with acute hypoxaemic respiratory failure, and collected clinical, biomarker, and treatment data.

The median age of patients was 62 years (51–72), 171 (67%) of 257 patients were men, 159 (62%) were Hispanic or Latino, and 13 (5%) were health-care workers. 212 (82%) patients had at least one chronic illness. 119 (46%) patients had obesity (defined as body-mass index [BMI]>=30), including 39 (71%) of 55 patients who were less than 50 years of age. Patients presented to hospital a median of 5 days (2–7) after symptom onset; black or African American and Hispanic or Latino patients presented later in their illness course than white patients.

Total

28 Day


Results

COVID-19 (death)

101

in-hospital mortality

Laboratory Findings

IL-6

Interleukin-6 (pg/mL) (per decile increase)

Not applicable

1 unit increase

Hazard ratio

1.110 (1.020-1.200)

No

Yes

Yes

Age, sex, hypertension, chronic cardiac disease, chronic obstructive pulmonary disease or interstitial lung disease, diabetes, Interleukin-6 (per decile increase), D-dimer (per decile increase)


Other information

none

Good

Yes

Go Back