Cai (2020)
Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China
https://doi.org/10.2337/dc20-0576
https://care.diabetesjournals.org/content/diacare/early/2020/05/12/dc20-0576.full.pdf
Patient characteristics
BMI (Overweight (24–27.9 kg/m2) vs. Normal (18.5–23.9 kg/m2))
COVID-19 (severe/fatal)
Odds ratio: 1.840 (0.990-3.430) Adjusted model

China

Descriptive (Case report/series)

Primary data collection

383

Data from all consecutively hospitalized COVID-19 patients from 11 January 2020 to 21 February 2020 at the Third People’s Hospital of Shenzhen were collected.

383 patients aged 18 years or above admitted in the Third People’s Hospital of Shenzhen was included in the current study. Of them, 53·1% were normal weight, 4·2% were underweight, 32·0% were overweight, and 10·7% were obese. There were more men in the obesity group than those in other obesity groups (78·1% versus 12·5% to 59·4%, P<0·001).

Total

38 Day


COVID-19 (severe/fatal)

91

Severe pneumonia was defined by the presence of any of the following conditions: 1) Significantly increased respiration rate (RR): RR >= 30 times/min; 2) Hypoxia: Oxygen saturation (resting state) ? 93%; 3) Blood gas analysis: PaO2 /FiO2>=300 mmHg; or 4) Occurrence of the respiratory or other organ failure that requires intensive care unit (ICU) monitoring and treatment, or shock


Patient characteristics

BMI

BMI, Kg/m2

Normal (18.5–23.9 kg/m2)

Overweight (24–27.9 kg/m2)


Odds ratio

1.840 (0.990-3.430)

No

No

Yes

BMI, gender


none

Average

Yes