Docherty (2020)
Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study
http://dx.doi.org/10.1136/ bmj.m1985
https://www.bmj.com/content/369/bmj.m1985
Comorbidities
Dementia (Present vs. Not present)
COVID-19 (death)
Hazard ratio: 1.400 (1.280-1.520) Adjusted model

United Kingdom

Prospective cohort study

Primary data collection

20133

Patients admitted to hospital with coronavirus disease 2019 (covid-19) in the United Kingdom during the growth phase of the first wave of this outbreak who were enrolled in the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World Health Organization (WHO) Clinical Characterisation Protocol UK (CCP-UK) study, and to explore risk factors associated with mortality in hospital

Median age 73 years (interquartile range 58-82, range 0-104). More men were admitted than women men 60%, n=12 068; women 40%, n=8065). The median duration of symptoms before admission was 4 days (interquartile range 1-8).

Total

2 Week


COVID-19 (death)

5165

mortality


Comorbidities

Dementia

none

Not present

Present


Hazard ratio

1.400 (1.280-1.520)

No

Yes

Yes

Multivariable cox proportional hazards model: age, sex, and major comorbidities)


none

Good

No