Yin (2020)
Correlation between Heart fatty acid binding protein and severe COVID-19: A case-control study
https://doi.org/10.1371/journal.pone.0231687
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231687#sec016
Laboratory Findings
Heart-fatty acid binding protein (Abnormal vs. Normal)
COVID-19 (severe/critical)
Odds ratio: 6.810 (5.230-8.400) Univariate analysis

China

Case-control study

Medical records

46

Patients tested for HFABP after the diagnosis of COVID-19, and monitored for HFABP during their hospital stay.

Age, mean (SD), yr 52.4 Male n=25

Total

4 Week


COVID-19 (severe/critical)

25

Severe COVID-19: confirmed as COVID-19 and meets any of the following criteria: 1. Respiratory distress, RR >= 30 times / min; 2. Means oxygen saturation <= 93%; Arterial blood oxygen partial pressure (PaO2) / oxygen concentration (FiO2) <= 300 mmHg (1 mmHg = 0.133 kPa).


Laboratory Findings

Heart-fatty acid binding protein

Heart-fatty acid binding protein (HFABP) > 7 ng / mL upon admission

Normal

Abnormal


Odds ratio

6.810 (5.230-8.400)

No

Yes

No

none


none

Poor

No