Pranata (2020)
Hypertension is associated with increased mortality and severity of disease in COVID-19 pneumonia: A systematic review, meta-analysis and meta-regression
32408793
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231906/
Comorbidities
Hypertension (Present vs. Not present)
COVID-19 (severe/critical)
Risk ratio: 1.640 (1.110-2.430) Univariate analysis

Indonesia

A systematic review, meta-analysis and meta-regression

review

1103

30 studies with a total of 6560 patients were included in the final qualitative and quantitative synthesis

Hypertension and poor outcome. This meta-analysis showed that hypertension was associated with increased composite poor outcome and its sub-group which comprises of mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), need for intensive care unit (ICU) care and disease progression in patients with COVID-19. Meta-regression analysis showed that the association between hypertension and increased composite poor outcome was influenced by (a) gender, but not age, cardiovascular diseases, diabetes and COPD.

0


COVID-19 (severe/critical)

137

Development of acute respiratory distress syndrome (ARDS)


Comorbidities

Hypertension

none

Not present

Present


Risk ratio

1.640 (1.110-2.430)

No

Yes

No

meta-analysis showed that hypertension was associated with increased composite poor outcome and its sub-group which comprises of mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), need for intensive care unit (ICU) care and disease progression in patients with COVID-19.


Meta-analysis - Hypertension and outcome

Average

Yes