Wang (2020)
Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China
https://doi.org/10. 1186/s13054-020-02895-6
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192564/
Laboratory Findings
Creatinine (1 unit increase (at admission) vs. Not applicable)
COVID-19 (death)
Odds ratio: 1.012 (0.987-1.037) Adjusted model

China

Retrospective observational study

Medical records

107

As of February 10, 2020, 544 patients were admitted to Zhongnan Hospital and Xishui Hospital, and 107 patients were discharged. The basic characteristics of the 107 patients (95 from Zhongnan and 12 from Xishui).

This study enrolled 107 discharged patients with COVID-19 which included 88 survivors and 19 non-survivors. The median age was 51?years (IQR, 36–65; range, 19–92years); 57 (53.3%) were male. The median times from first symptoms to hospital admission, dyspnea, and ARDS were 7?days (IQR, 3.5–9), 5.5?days (IQR, 2–9.3), and 7.5?days (IQR, 4.3–11), respectively. The median length of hospital stay was 11days (IQR, 7–15).

Median

11 Day


COVID-19 (death)

19

Non-survivors - Non-survivors were more likely to have underlying comorbidities, including hypertension and other cardiovascular disease. Compared with the survivors, non-survivors were more likely to report dyspnea and diarrhea at presentation. At hospital admission, the respiratory rate was higher in survivors than in non-survivors. Similarly, the mean arterial pressure was higher in non-survivors than in survivors. Vital signs including heart rate, respiratory rate, and mean arterial pressure were collected at admission


Laboratory Findings

Creatinine

Creatinine concentration. In non-survivors, blood urea and creatinine levels progressively increased until death.

Not applicable

1 unit increase (at admission)


Odds ratio

1.012 (0.987-1.037)

No

No

Yes

Age, gender, Hypertension, cardiovascular disease, Creatinine concentration


none

Average

Yes