Liu (2020)
Association between Initial Chest CT or Clinical Features and Clinical Course in Patients with Coronavirus Disease 2019 Pneumonia
Radiological finding on admission (Ground-glass opacities and linear opacities vs. Not present)
Hospital discharge
Hazard ratio: 1.600 (0.110-22.860) Adjusted model


Retrospective observational study

Medical records


A total of 72 patients with COVID-19 confirmed by nucleic acid test were identified from three hospitals in Xi'an, Shaanxi province, China. Baseline chest CT and laboratory examination results were collected.

72 patients admitted with COVID-19 pneumonia (39 men, 46.2 ± 15.9 years) were retrospectively analyzed. Three patients had uncomplicated illness, 61 patients had mild disease, and 8 patients had severe disease. Fourteen patients initially had negative nucleic acid tests that were subsequently positive. Patients had been admitted to the hospital for 4 to 27 days (median, 17 days). Thirty-two patients recovered and were discharged during the study period, and the median length of the clinical course was 15.5 days (range, 9 to 25 days). For those who remained hospitalized at the end of this investigation, the median length of hospitalization was 17.5 days (range, 4 to 27 days). No patient died during the study period. Among those with COVID-19, the severe patients were older than patients with mild and uncomplicated illness (P < 0.001).


4 Week

Hospital discharge


Patients recovered and were discharged during the study period. The median length of the clinical course was 15.5 days (range, 9 to 25 days)


Radiological finding on admission

The initial chest CT findings were compared among the disease severity groups (uncomplicated, mild, and severe).

Not present

Ground-glass opacities and linear opacities

Hazard ratio

1.600 (0.110-22.860)




Age, onset time, lesion characteristics like GGO, GGO and consolidation, exhibited consolidation, GGO and linear opacities, consolidation and linear opacities, all three signs GGO, consolidation and linear opacities, number of lung lobes affected, and bilateral involvement, the lung severity score on baseline CT. Laboratory testing - Lymphocyte count.