Yu (2020)
Association Between Clinical Manifestations and Prognosis in Patients with COVID-19
https://doi.org/10.1016/j.clinthera.2020.04.009
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183954/
Patient characteristics
BMI (1 unit increase vs. Not applicable)
COVID-19 (severe/critical)
Odds ratio: 1.285 (1.045-1.581) Adjusted model

China

Cross-sectional study

Medical records

95

All consecutive patients with confirmed 2019-nCoV infections who were diagnosed in the Dongguan People's Hospital and Nanfang Hospital, Southern Medical University, from January 2020 to February 2020 were enrolled.

All patients' clinical, laboratory, and radiologic characteristics, as well as treatment outcome data, were obtained through medical record extraction. a ) A total of 95 patients infected with 2019-nCoV were enrolled. Seventy-three had pneumonia based on the CT findings, and 22 did not have pneumonia. b) Using the ARDS definition, patients were divided into an ARDS group (n = 24) and a non-ARDS group (n = 71) c) A total of 70 patients underwent CT scanning repeatedly after 1 week of treatment. Based on the findings obtained after comparison with the first CT scan, patients were divided into the pneumonia exacerbation group (n = 19) and the pneumonia relief group (n = 51).

Total

30 Day


COVID-19 (severe/critical)

19

disease exacerbation in 2019-nCoV–infected patients after treatment


Patient characteristics

BMI

kg/m2

Not applicable

1 unit increase


Odds ratio

1.285 (1.045-1.581)

No

Yes

Yes

Risk adjusted for Body Mass Index (BMI) and Tobacco smoking for Disease exacerbation group.


Factors associated with pneumonia exacerbation in patients with coronavirus disease 2019

Average

Yes