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Article data
Liu (2020)
Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19
https://dx.doi.org/10.1016%2Fj.jcv.2020.104370
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194648/

Results
Laboratory Findings
IL-6 (Abnormal vs. Normal)
COVID-19 (severe/critical)
Hazard ratio: 2.375 (1.058-5.329) Adjusted model

Study characteristics

China

Retrospective cohort study

Medical records

140

patients with COVID-19

A total of 140 patients with COVID-19 were included in this study (one patient was excluded because of massive gastrointestinal hemorrhage). In the study population, 107 patients were assigned to a mild group (MG) and 33 patients were allocated to a severe group (SG). There was no significant difference in the male to female ratio between the two groups. The median age was 65.5 years (range, 23–96). The average age was significantly higher in the SG than in the MG (P<0.0001)

Total

54 Day


Results

COVID-19 (severe/critical)

33

Patients with severe disease were categorized based on the seventh edition of the Chinese National Health Commission and should meet any of the following criteria: 1) shortness of breath, respiratory rate >=30 beats per min; 2) oxygen saturation <=93 % at rest; 3) arterial oxygen partial pressure (PaO2)/oxygen concentration (FiO2) <=300 mmHg (1mmHg=0.133KPa); and 4) lung images showing obvious progress of lesion size >50 % within 24-48h.

Laboratory Findings

IL-6

IL-6>32.1 pg/mL vs normal

Normal

Abnormal

Hazard ratio

2.375 (1.058-5.329)

No

Yes

Yes

Age, IL-6, CRP and PCT


Other information

none

Average

Yes

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