Wu (2020)
Early antiviral treatment contributes to alleviate the severity and improve the prognosis of patients with novel coronavirus disease (COVID-19)
32220033
https://www.ncbi.nlm.nih.gov/pubmed/32220033
Laboratory Findings
D-dimer (Abnormal at admission vs. Normal)
COVID-19 (severe/critical)
Odds ratio: 3.200 (1.750-5.880) Univariate analysis

China

Retrospective cohort study

Medical records

280

A total of 280 eligible COVID-19 patients were recruited from four hospitals in Jiangsu and Anhui Province, China.

Among the enrolled cases, the overall mean age was 43.12 years (SD 19.02). 84 patients (30.00%) were aged 50-64 years, which accounted for the highest proportion. The proportion of patients aged under 18 years, 18-24 years and 25-49 years were 12.50%, 5.00% and 27.86%, respectively. Moreover, 49 patients (17.50%) were mild type, 148 patients (52.86%) were moderate type, 75 patients (26.79%) were severe type and 8 patients (2.85%) were critically ill.

Median

0


COVID-19 (severe/critical)

83

none


Laboratory Findings

D-dimer

none

Normal

Abnormal at admission


Odds ratio

3.200 (1.750-5.880)

No

No

No

Adjusted to age, Comorbidity, Time from illness onset to antiviral


none

Good

Yes