Of 343 eligible patients, the median age was 62 years (IQR, 48?69), ranging from 18 years to 92 years. A total of 37.6% (129/343) patients were older than 65 years and 50.3% (174/343) patients were female. According to the optimum cutoff value, 276 patients’ D-dimer levels on admission were less than 2.0 µg/mL, and 67 patients had D-dimer levels over 2.0 µg/mL. Compared with those patients with D-dimer levels below 2.0 µg/mL, patients with D-dimer levels >=2.0 µg/mL had a higher incidence of underlying disease, such as diabetes (P = .007), hypertension (P < .001), coronary heart disease (P = .02), and stroke history (P < .001). Additionally, lower level of lymphocyte (P < .001), hemoglobin (P = .003), platelet count (P = .009), and higher level of neutrophil (P < .001), C-reactive protein (P < .001), and prothrombin time (P < .001) were also observed in those with D-dimer levels >=2.0 µg/mL.