Xu (2020)
Risk factors for severe corona virus disease 2019 (COVID-19) patients : a systematic review and meta analysis
https://doi.org/10.1101/2020.03.30.20047415
https://www.medrxiv.org/content/10.1101/2020.03.30.20047415v1
Patient characteristics
Smoking (Present vs. Not present)
COVID-19 (severe/critical)
Odds ratio: 1.400 (0.650-3.010) Univariate analysis

China

Systematic review and meta analysis

Medical records

4062

20 articles (N=4062 participants) were included

All articles were observational studies. All the subjects are from China, including more than 30 provinces and cities. The study period spans from 11 December 2019 to 23 February 2020. About the comparison of mild and severe patients, 15 studies described patient characteristics, 15 studies described comorbidities, 8 studies described vital signs, 17 studies compared symptoms and 19 studies described laboratory findings.

0


COVID-19 (severe/critical)

412

Patients with COVID-19


Patient characteristics

Smoking

none

Not present

Present


Odds ratio

1.400 (0.650-3.010)

No

No

No

-


Number of cases and patients in reference and comparison are not reported. A fixed-effects model was used on 3 articles involving 412 patients to analyze the risk factors of smoking showed that there was no significant correlation between smoking and the severe pneumonia (OR = 1.4 [0.65, 3.01]). I1 = 0%

Average

No