Xu (2020)
Risk factors for severe corona virus disease 2019 (COVID-19) patients : a systematic review and meta analysis
https://doi.org/10.1101/2020.03.30.20047415
https://www.medrxiv.org/content/10.1101/2020.03.30.20047415v1
Laboratory Findings
Creatine kinase (1 unit increase vs. Not applicable)
COVID-19 (severe/critical)
Weighted Mean Difference: 23.550 (17.080-30.020) Univariate analysis

China

Systematic review and meta analysis

Medical records

4062

20 articles (N=4062 participants) were included

All articles were observational studies. All the subjects are from China, including more than 30 provinces and cities. The study period spans from 11 December 2019 to 23 February 2020. About the comparison of mild and severe patients, 15 studies described patient characteristics, 15 studies described comorbidities, 8 studies described vital signs, 17 studies compared symptoms and 19 studies described laboratory findings.

0


COVID-19 (severe/critical)

213

Severe patients with COVID-19


Laboratory Findings

Creatine kinase

(IU/L)

Not applicable

1 unit increase


Weighted Mean Difference

23.550 (17.080-30.020)

No

Yes

No

-


Number of cases and patients in reference and comparison are not reported. The results is based on meta-analysis from 3 studies.

Average

No