China
Retrospective cohort study
Medical records
645
645 patients confirmed with SARS-CoV-2 infection between Jan 17 to Feb 8, 2020 underwent CT examination or X-ray, in Zhejiang, China.
The diagnosis of novel coronavirus disease (COVID-19) was based on WHO interim guidance(WorldHealthOrganization, 2020c). And subtype definition of COVID-19 was according to the diagnosis and treatment scheme for SARS-CoV-2 of China (5th edition)
0
COVID-19 (severe/critical)
64
For mild type: slight clinical symptoms without no pneumonia presentation in imaging. For common type: manifestations such as fever and/or respiratory presentation with pneumonia under radiography. For severe type (meeting any of the followings ): (1) dyspnea, RR? 30 times/minute; (2) finger oxygen saturation under resting?93%? (3) arterial PaO2/FiO2 <=300mmHg(1mmHg=0.133kpa). For critical type (meeting any of the followings): (1) respiratory failure and need mechanical ventilation; (2) shock; (3) combined with other organ failure and an intensive care unit is needed
Laboratory Findings
Lymphocytes
Count (10^9/L)
Not applicable
1 unit increase
Odds ratio
0.260 (0.090-0.700)
Yes
No
Symptoms of muscle ache, shortness of breath, nausea and vomiting, higher serum creatinine level, and lower lymphocytes level
Muscle ache, shortness of breath, nausea and vomiting, lower lymphocytes levels and higher serum creatinine and radiograph score at admission were predictive factors for severe/critical subtype.
Good