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Article data
Du (2020)
Predictors of Mortality for Patients with COVID-19 Pneumonia Caused by SARS-CoV-2: A Prospective Cohort Study
https://doi.org/10.1183/13993003.00524-2020
https://erj.ersjournals.com/content/early/2020/04/01/13993003.00524-2020

Results
Laboratory Findings
Cardiac troponin (Abnormal vs. Normal)
COVID-19 (death)
Odds ratio: 4.080 (1.170-14.250) Adjusted model

Study characteristics

China

Prospective cohort study

Medical records

179

179 patients who were hospitalised to Wuhan Pulmonary Hospital between December 25, 2019 and February 7, 2020, of whom 136 (76%) were diagnosed definitely as having COVID-19 pneumonia with positive SARS-CoV-2 test result and the remaining 43 (24%) were diagnosed clinically.

The mean time between onset of symptoms and hospitalisation was 9.7 days (sd, 4.3 days). The mean age was 57.6 years (sd, 13.7 years; range, 18-87 years), and 97 (54.2%) were men. Of 179 patients, 21 (11.7%) worsened in a short period of time and died of multiple organ failure, especially respiratory failure and heart failure, and the mean duration from admission to death was 13.7?days (sd, 8.3 day; rang, 3 - 33 days)

0


Results

COVID-19 (death)

21

Mortality of COVID-19 pneumonia patients

Laboratory Findings

Cardiac troponin

Cardiac troponin >=0.05

Normal

Abnormal

Odds ratio

4.080 (1.170-14.250)

No

Yes

Yes

Multivariable logistic regression model which selected four variables that were predictive of mortality, including age group ?65?years, cardiovascular or cerebrovascular diseases, CD3+CD8+ T cells ?75?cellÂ??L?1, and cardiac troponin I?0.05?ngÂ?mL?1


Other information

p value for OR: p<0.001. They identified four risk factors, age >= 65 years, preexisting concurrent cardiovascular or cerebrovascular diseases, CD3+CD8+ T cells <= 75 cell.uL-1, and cardiac troponin I >= 0.05 ngÂ?mL-1, especially the latter two factors, were predictors for mortality of COVID-19 pneumonia patients.

Average

No

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