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Article data
Xu (2020)
Factors associated with prolonged viral RNA shedding in patients with COVID-19
https://doi.org/10.1093/cid/ciaa351
https://www.ncbi.nlm.nih.gov/pubmed/32271376

Results
Treatment
Treatment for COVID-19 (Treated with corticosteroid vs. Not received)
Prolonged duration of SARS-CoV-2 shedding
Odds ratio: 1.380 (0.520-3.650) Adjusted model

Study characteristics

China

Retrospective cohort study

Medical records

113

Patients with confirmed SARS-CoV-2 infection admitted to the First Affiliated Hospital, School of Medicine, Zhejiang University and the Shenzhen Third People's Hospital

the median age was 52 years, and 58.4% were male. Inclusion criteria: 1. disease duration over 21 days without viral RNA clearance; 2. viral RNA clearance occurred within 21 days; 3. death occurred within 21 days. According to the criteria, 47 patients were excluded as they were less than 21 days since illness onset and without viral RNA clearance. And one patient was excluded, as she was transferred to the local hospital without viral RNA clearance

Not stated

0


Results

Prolonged duration of SARS-CoV-2 shedding

76

prolonged viral RNA shedding >=15 days after illness onset

Treatment

Treatment for COVID-19

Corticosteroid treatment

Not received

27

49

Treated with corticosteroid

49

64

Odds ratio

1.380 (0.520-3.650)

No

No

Yes

risk was adjusted for age, sex, hypertension, time from illness onset to hospitalization, severe illness at admission, critical illness in hospitalization, and invasive mechanical ventilation


Other information

None

Average

Yes

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