Wang (2020)
Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis
32267833
https://www.ncbi.nlm.nih.gov/pubmed/32267833
Comorbidities
Cardiovascular disease (Present vs. Not present)
COVID-19 (severe/critical)
Odds ratio: 3.890 (1.640-9.220) Univariate analysis

China

Meta-analysis

Medical records

1558

A literature search was performed using the electronic platforms (PubMed, Cochrane Library, Embase, and other databases) to obtain relevant research studies published up to March 1, 2020.

A total of 1558 samples from 6 retrospective studies were enrolled in this meta-analysis. Studies: C.Huang, D.Wang, W.Guan, W.Liu, X.Xu, J.Zhang

0


COVID-19 (severe/critical)

324

The judgment criteria for severe and non-severe patients included in the study were not uniform


Comorbidities

Cardiovascular disease

Cerebrovascular disease refers to a group of conditions, diseases, and disorders

Not present

Present


Odds ratio

3.890 (1.640-9.220)

No

Yes

No

Hypertension, diabetes, COPD, cardiovascular disease, and cerebrovascular disease are major risk factors for patients with COVID-19. Knowledge of these risk factors can be a resource for clinicians in the early appropriate medical management of patients with COVID-19.


The meta-analysis revealed no correlation between increased risk of COVID-19 and liver disease, malignancy, or renal disease.

Good

Yes