Zhang (2020)
Myocardial injury is associated with in-hospital mortality of confirmed or
https://doi.org/10.1101/2020.03.21.20040121
https://doi.org/10.1101/2020.03.21.20040121
Patient characteristics
Age (1 year increase vs. Not applicable)
COVID-19 (severe/critical)
Hazard ratio: 1.010 (0.940-1.090) Adjusted model

China

Retrospective cohort study

Medical records

110

Investigate the association between cardiac injury and in-hospital mortality of patients with confirmed or suspected COVID-19.

Demographic, clinical, treatment, and laboratory data of consecutive confirmed or suspected COVID-19 patients admitted in Wuhan No.1 Hospital from 25th December, 2019 to 15th February, 2020 were extracted from electronic medical records and were retrospectively reviewed and analyzed.

Total

10 Day


COVID-19 (severe/critical)

48

COVID-19 (progression): Myocardial injury is associated with in-hospital mortality of confirmed or suspected COVID-19


Patient characteristics

Age

The mean age of 48 patients included was 70.58?13.38 year old and 15?31.3%?patients were female. After a median follow-up of 10 days, 17 patients (17/48, 35.4%) died while 29 (29/48, 60.4%) and 2 (2/4

Not applicable

1 year increase


Hazard ratio

1.010 (0.940-1.090)

No

No

Yes

Cardiac injury defined by hs-cTnI elevation and elevated d-dimer on admission were risk factors for in-hospital death, while higher SpO2 could be seen as a protective factor, which could help clinicians to identify patients with adverse outcome at the early stage of COVID-19.


investigate the association between cardiac injury and in-hospital mortality of patients with confirmed or suspected COVID-19.

Good

No