Wu (2020)
Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China
https://doi.org10.1001/jamainternmed.2020.0994
https://www.ncbi.nlm.nih.gov/pubmed/32167524
Laboratory Findings
Urea (Abnormal at admission vs. Normal)
COVID-19 (severe/fatal)
Hazard ratio: 1.130 (1.090-1.180) Univariate analysis

China

Retrospective cohort study

Medical records

201

Patients aged 21 to 83 years with confirmed COVID-19 pneumonia hospitalized at Jinyintan Hospital in Wuhan, China.

All patients were diagnosed with COVID-19 pneumonia according to World Health Organization interim guidance. According tohospitaldata, patients were admitted from December 25, 2019, to January 26, 2020.

0


COVID-19 (severe/fatal)

84

Development of ARDS and death among those with ARDS. World Health Organization interim guidance was used to define ARDS.


Laboratory Findings

Urea

Normal

Abnormal at admission


Hazard ratio

1.130 (1.090-1.180)

No

Yes

No

Bivariate Cox proportional hazard ratio (HR) models were used to determine HRs and 95% CIs between individual factors on the development of ARDS or progression from ARDS to death.


none

Average

No