Ji (2020)
Prediction for Progression Risk in Patients with COVID-19 Pneumonia: the CALL Score
https://doi.org/10.1093/cid/ciaa414
https://academic.oup.com/cid/article/doi/10.1093/cid/ciaa414/5818317
Laboratory Findings
LDH (Abnormal vs. Normal)
COVID-19 (severe/critical)
Hazard ratio: 2.500 (1.200-5.200) Adjusted model

China

Retrospective observational study

Medical records

208

Consecutive confirmed patients with COVID-19

Overall, 208 consecutive confirmed patients with COVID-19 presented to two centers were enrolled from January 20 through February 22, 2020, the follow-up period ended in March 18, 2020.

Total

25 Day


COVID-19 (severe/critical)

40

COVID-19 (progression): Severe COVID-19 was defined as at least one of the followings, respiratory rate ? 30 breaths/min, resting oxygen saturation ? 93%, PaO2/FiO2 ? 300 mmHg or requirement of mechanical ventilation. Progression to severe COVID-19 was development of one or more of the above or worsening of lung CT findings during the observation period.


Laboratory Findings

LDH

250-500 U/L

Normal

Abnormal


Hazard ratio

2.500 (1.200-5.200)

No

Yes

Yes

D-dimer, comorbidity, older age, higher LDH and lower lymphocyte


Using the CALL score model, clinicians can improve the therapeutic effect and reduce the mortality of COVID-19 with more accurate and reasonable resolutions on medical resources.

Good

Yes