Liu (2020)
Risk Factors Associated with Disease Severity and Length of Hospital Stay in COVID-19 Patients
https://doi.org/10.1016/j.jinf.2020.04.008
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162771/pdf/main.pdf
Comorbidities
Hypertension (Present vs. Not present)
COVID-19 (severe/critical)
Odds ratio: 3.590 (1.010-12.800) Adjusted model

China

Retrospective cohort study

Medical records

90

Consecutive patients with moderate or severe COVID-19 discharged from the general wards of Renmin Hospital of Wuhan University between 5 February 2020 to 14 March 2020

-

0


COVID-19 (severe/critical)

34

Patients with severe pneumonia


Comorbidities

Hypertension

-

Not present

Present


Odds ratio

3.590 (1.010-12.800)

No

Yes

Yes

Multivariate logistic regression analysis- age, hypertension, dyspnea, fatigue, anorexia/lethargic, C-reactive protein, neutrophil count, lymphocyte count


Taking together, we report hypertension, increased CRP and lymphopenia as independent risk factors for disease severity

Average