Wu (2020)
Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China
https://doi.org10.1001/jamainternmed.2020.0994
https://www.ncbi.nlm.nih.gov/pubmed/32167524
Laboratory Findings
Globulin (Abnormal at admission vs. Normal)
COVID-19 (death)
Hazard ratio: 1.910 (1.010-3.610) Univariate analysis

China

Retrospective cohort study

Medical records

201

Patients aged 21 to 83 years with confirmed COVID-19 pneumonia hospitalized at Jinyintan Hospital in Wuhan, China.

All patients were diagnosed with COVID-19 pneumonia according to World Health Organization interim guidance. According tohospitaldata, patients were admitted from December 25, 2019, to January 26, 2020.

0


COVID-19 (death)

84

Development of ARDS and death among those with ARDS. World Health Organization interim guidance was used to define ARDS.


Laboratory Findings

Globulin

none

Normal

Abnormal at admission


Hazard ratio

1.910 (1.010-3.610)

No

Yes

No

Bivariate Cox proportional hazard ratio (HR) models were used to determine HRs and 95% CIs between individual factors on the development of ARDS or progression from ARDS to death.


none

Average

Yes