China
Ambispective Observational Study
Medical records
548
548 hospitalized COVID-19 patients
none
Total
15 Day
COVID-19 (death)
78
Death within 15 days of hospitalization.
Laboratory Findings
WBC
WBC count (reference > 10 x 109/L)
>10×10^9/L
<4×10^9/L
Hazard ratio
0.700 (0.270-1.850)
No
Yes
Risk was adjusted for Age, oxygen saturation (SaO2), WBC, Lymphocyte (count and time), LDH, and multiorgan dysfunction, Glucocorticoid treatment, lopinavir/ritonavir treatment, arbidol treatment, ribavirin treatment.
14.2% patients of this cohort reached the primary endpoint of death within 15-day hospitalization. Aging, hypoxia, lymphopenia, high LDH level and multiple organ dysfunction were associated with increased 15-day in-hospital mortality from COVID-19. Lopinavir/ritonavir was associated with decreased mortality. Among the critically ill patients, the hazard ratio was not reduced in those receiving invasive ventilation versus non-invasive ventilation.
Good