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COVID-19 (death)

78

Death within 15 days of hospitalization.

Treatment

Treatment for COVID-19

Treatment with ribavirin (yes vs. no)

Not received

Ribavirin received

Hazard ratio

1.420 (0.670-3.030)

No

No

Yes

Risk was adjusted for Age, oxygen saturation (SaO2), WBC, Lymphocyte (count and time), LDH, and multiorgan dysfunction, Glucocorticoid treatment, lopinavir/ritonavir treatment, arbidol treatment, ribavirin treatment.

14.2% patients of this cohort reached the primary endpoint of death within 15-day hospitalization. Aging, hypoxia, lymphopenia, high LDH level and multiple organ dysfunction were associated with increased 15-day in-hospital mortality from COVID-19. Lopinavir/ritonavir was associated with decreased mortality. Among the critically ill patients, the hazard ratio was not reduced in those receiving invasive ventilation versus non-invasive ventilation.

Good

Yes