Cai (2020)
COVID-19 in a designated infectious diseases hospital outside Hubei Province, China.
Patient characteristics
BMI (1 unit increase in BMI vs. Not applicable)
COVID-19 (severe/critical)
Odds ratio: 1.170 (1.030-1.340) Adjusted model


Retrospective cohort study

Medical records


All the hospitalized COVID-19 patients in the only referral hospital in Shenzhen City, China, from January 11, 2020, to February 6, 2020 were enrolled in this retrospective cohort study.

The median age of all patients was 47 years (IQR, 33?61). 50% of all patients were male. The median body mass index (BMI) was 23.05 (20.92?25.44). 69.1% patients were imported cases from Wuhan City, the other 12.4% were from other areas of Hubei Province, 4.4% had not been to Hubei Province but were infected by people from Hubei Province, and the remaining 14.1% had no clear contact history. The most common symptom at onset of illness was fever (218 [73.15%] patients), but 10.1% had no symptoms at the onset. For the 30 people with no symptoms, 12 cases had early mild lesions, seven cases had advanced lesions, and only eleven cases had a normal CT. There were no remarkable values for eosinophils.


29 Day

COVID-19 (severe/critical)


Pulmonary imaging showed that the lesions progressed more than 50% within 24-48 hours, indicating that the patients were severe. The CT manifestations of severe patients were diffuse lesions in both lungs, with uneven density, high ground glass density shadow, and consolidation, accompanied by fibrous streak shadow.

Patient characteristics


BMI, kg/m^2.BMI is the only significant variable (adjusted hazard ratio P = .04).

Not applicable

1 unit increase in BMI

Odds ratio

1.170 (1.030-1.340)




Risk was adjusted for Age, gender, contact history, fever, hypertension, BMI, Lymphocyte, C-reactive protein, interleukin-6, and Image changes of lung CT.

Mortality may be lowered when cases are relatively mild, and there are sufficient medical resources to care and treat the disease. The crude numbers are very different.