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Article data
Zhao (2020)
The impact of COPD and smoking history on the severity of Covid-19: A systemic review and meta-analysis.
https://doi.org/10.1002/jmv.25889
https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmv.25889

Results
Patient characteristics
Smoking (Present vs. Not present)
COVID-19 (severe/fatal)
Odds ratio: 1.980 (1.290-3.050) Univariate analysis

Study characteristics

China

Meta Analysis

Medical records

2002

Overall 11 case-series, published either in Chinese or English language with a total of 2002 cases were included in the study.

Pooling the clinical data of the 11 studies included in this meta-analysis resulted in a total of 2002 patients, 334 meetings the definition of severe Covid-19. Out of the 11 studies, one study reported only on the smoking history16, and four others reported only on the presence of COPD. The rest of the studies reported both, the smoking history and the presence of COPD.

0


Results

COVID-19 (severe/fatal)

334

Explore the risk of severe Covid-19 in patients with pre-existing chronic obstructive pulmonary disease (COPD) and ongoing smoking history.

Patient characteristics

Smoking

The pooled OR shows that smoking increases the risk of severe Covid-19 (Fixed effect model, OR=1.98, 95% CI: 1.29-3.05) by around 2-folds

Not present

Present

Odds ratio

1.980 (1.290-3.050)

No

Yes

No

[ventilation/ICU/death - COPD, Smoking] and [severe/progression - COPD, Smoking]


Other information

Fixed effect model

Good

No

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