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Article data
Zhou (2020)
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
https://doi.org/10.1016/S0140-6736(20)30566-3
https://www.ncbi.nlm.nih.gov/pubmed/32171076

Results
Complications
Sequential Organ Failure Assessment (SOFA) score (1 unit increase vs. SOFA score: 0)
COVID-19 (death)
Odds ratio: 5.650 (2.610-12.230) Adjusted model

Study characteristics

China

Retrospective cohort study

Medical records

191

All adult patients who were diagnosed with COVID-19 according to WHO interim guidance were screened, and those who died or were discharged between Dec 29, 2019 (ie, when the first patients were admitted), and Jan 31, 2020, were included in our study.

Two cohorts of adult inpatients (>=18 years old) from Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan, China).

0


Results

COVID-19 (death)

54

patients died during hospitalisation

Complications

Sequential Organ Failure Assessment (SOFA) score

Sequential Organ Failure Assessment (SOFA) scores

SOFA score: 0

0

0

1 unit increase

0

0

Odds ratio

5.650 (2.610-12.230)

No

Yes

Yes

We chose lymphocyte count, d-dimer, SOFA score, coronary heart disease, and age as the five variables for our multivariable logistic regression model. We excluded variables from the univariable analysis if their between-group differences were not significant, if their accuracy was unconfirmed (eg, exposure, which was self-reported), if the number of events was too small to calculate odds ratios, and if they had colinearity with the SOFA score.


Other information

none

Average

Yes

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