Sun (2020)
Risk factors for mortality in 244 older adults with COVID?19 in Wuhan, China: a retrospective study
Laboratory Findings
Serum N-terminal pro B-type natriuretic peptide (NT-proBNP) (1 unit increase (at admission) vs. Not applicable)
COVID-19 (death)
Odds ratio: 1.000 (0.999-1.001) Adjusted model


Retrospective observational study

Medical records


Patients ? 60 years of age, who were diagnosed with COVID-19 with definite outcomes (discharged or died in hospital) by March 5, 2020, were enrolled.

The diagnosis of all included patients was confirmed according to the Diagnosis and Treatment Guideline for COVID-19 published by the National Health Commission of People’s Republic of China


COVID-19 (death)


Patients who died of COVID-19 and related complications in the hospital were enrolled as the deceased group, while those who fulfilled the criteria for cure of COVID-19, as per the guideline5 and discharged from hospital, were enrolled as the discharged group

Laboratory Findings

Serum N-terminal pro B-type natriuretic peptide (NT-proBNP)

NT-proBNP (x102 pg/mL)

Not applicable

1 unit increase (at admission)

Odds ratio

1.000 (0.999-1.001)




Age (years), Sex , SpO2, Heart rate, Respiratory rate, Consciousness disorders, Hypertension, Previous respiratory diseases, oxygen saturation; white blood cells; lymphocytes; amino-terminal pro-brain natriuretic peptide; procalcitonin; hs-TnI, high-sensitivity cardiac troponin I; alanine aminotransferase; aspartate aminotransferase, estimated glomerular filtration rate; high-sensitivity C-reactive protein