Yang (2020)
The effect of corticosteroid treatment on patients with coronavirus infection: a systematic review and meta-analysis
32283144
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195158/
Treatment
Treatment for COVID-19 (Treated with corticosteroid vs. Not received)
COVID-19 (severe/critical)
Risk ratio: 2.360 (1.310-4.280) Adjusted model

China

Systematic Review and Meta-Analysis

Registry

71

A total of 5270 patients from 15 studies were included in this meta-analysis - from January 1, 2002 to March 15, 2020 Wang and Huang articles were selected to describe the pooled effect of corticosteroid use

The inclusion criteria in this meta-analysis were as follows: (1) subjects in each study were patients with coronavirus infection; (2) the patients were divided into the experimental group using corticosteroids and the control group not using corticosteroids; (3) the outcomes included the use of corticosteroids in critical and non-critical patients, mortality, length of stay (LOS) and adverse reactions to corticosteroids. Exclusion criteria: (1) the same patients were enrolled in different articles; (2) commentaries, editorials, case reports, letters and family-based studies; and (3) patients in studies were under 18?years old.

0


COVID-19 (severe/critical)

32

Severe cases are those who were admitted to ICU


Treatment

Treatment for COVID-19

Use of corticosteroids

Not received

Treated with corticosteroid


Risk ratio

2.360 (1.310-4.280)

No

Yes

Yes

Treatment - Corticosteroid


none

Average

Yes