COVID Risk | Literature database and meta-analysis page 6

Last update : 2021-08-05 08:37:15 (GMT+2) | 276 factors investigated | 1766 estimates included | 219 articles processed | QC progress: 50%

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Associated factors

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Green: significant protective factor
Red: significant risk factor
^§ adjusted estimate (see article details)
^† estimated using data reported in the article

Outcome	Risk category	Risk [exposed vs. unexposed]	Risk estimate (95% CI)	Author [URL]	View	QC
COVID-19 (death)	Patient characteristics	Age [60-69 years vs. 50-59 years]	Hazard ratio: 2.090 (1.840-2.380) ^§	The OpenSAFELY Collaborative
COVID-19 (death)	Patient characteristics	Age [40-49 years vs. 50-59 years]	Hazard ratio: 0.310 (0.250-0.390) ^§	The OpenSAFELY Collaborative
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with aspirin vs. Not received]	Odds ratio: 1.250 (0.660-2.390) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with fibrates vs. Not received]	Odds ratio: 0.040 (0.001-29.260) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with Statins vs. Not received]	Odds ratio: 2.500 (1.480-4.210) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with insulin vs. Not received]	Odds ratio: 2.950 (1.650-5.260) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with DPP.4 inhibitor vs. Not received]	Odds ratio: 6.180 (2.500-15.270) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with thiazolidinediones vs. Not received]	Odds ratio: 0.350 (0.110-1.130) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with insulin secretagogues vs. Not received]	Odds ratio: 1.290 (0.720-2.290) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with biguanides vs. Not received]	Odds ratio: 1.020 (0.610-1.690) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with glycosidase inhibitors vs. Not received]	Odds ratio: 0.180 (0.100-0.320) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with beta-blockers vs. Not received]	Odds ratio: 0.790 (0.450-1.400) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with diuretics vs. Not received]	Odds ratio: 0.320 (0.190-0.570) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with calcium channel blocker vs. Not present]	Odds ratio: 1.670 (1.220-2.290) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with ARBs vs. Not received]	Odds ratio: 0.240 (0.170-0.340) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with ACEi vs. Not received]	Odds ratio: 0.650 (0.260-1.570) ^§	Yan
COVID-19 (any condition)	Treatment	Concomitant medication [Treated with Glucocorticoids vs. Not received]	Odds ratio: 1.200 (0.490-2.940) ^§	Yan
COVID-19 (any condition)	Comorbidities	Cancer [Present vs. Not present]	Odds ratio: 0.990 (0.540-1.810) ^§	Yan
COVID-19 (any condition)	Comorbidities	Cardiovascular or cerebrovascular disease [Present vs. Not present]	Odds ratio: 2.140 (1.250-3.660) ^§	Yan
COVID-19 (any condition)	Comorbidities	Hypertension [Present vs. Not present]	Odds ratio: 1.030 (0.820-1.290) ^§	Yan
COVID-19 (any condition)	Comorbidities	Diabetes [Present vs. Not present]	Odds ratio: 1.540 (1.150-2.060) ^§	Yan
COVID-19 (any condition)	Comorbidities	HBV [Present vs. Not present]	Odds ratio: 1.260 (0.890-1.790) ^§	Yan
COVID-19 (any condition)	Patient characteristics	Smoking [Present vs. Not present]	Odds ratio: 0.760 (0.570-1.010) ^§	Yan
COVID-19 (death)	Patient characteristics	Age [18-39 years vs. 50-59 years]	Hazard ratio: 0.070 (0.050-0.100) ^§	The OpenSAFELY Collaborative
COVID-19 (death)	Comorbidities	Immunocompromised [Present vs. Not present]	Odds ratio: 2.106 (1.085-4.087) ^§	Borghesi
COVID-19 (death)	Patient characteristics	Age [1 year increase vs. Not applicable]	Odds ratio: 1.081 (1.046-1.118) ^§	Borghesi
COVID-19 (death)	Findings	Radiological finding during hospitalization [1 unit increase in Brixia score vs. Not applicable]	Odds ratio: 1.327 (1.200-1.472) ^§	Borghesi
COVID-19 (Acute Kidney Injury)	Treatment	Concomitant medication [Treated with ACEi/ARB vs. Not received]	Odds ratio: 0.870 (0.730-1.040) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Intervention	Vasoactive medication [Administered vs. Not administered]	Odds ratio: 4.530 (2.880-7.130) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Intervention	Invasive mechanical ventilation [Used vs. Not used]	Odds ratio: 10.700 (6.810-16.700) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Comorbidities	Cancer [Present vs. Not present]	Odds ratio: 1.090 (0.820-1.450) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Patient characteristics	BMI [Obesity (>=30 kg/m2) vs. Normal (<25 kg/m2)]	Odds ratio: 1.110 (0.940-1.310) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Comorbidities	Cardiovascular disease [Present vs. Not present]	Odds ratio: 1.480 (1.220-1.800) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Comorbidities	Hypertension [Present vs. Not present]	Odds ratio: 1.250 (1.040-1.500) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Comorbidities	Diabetes [Present vs. Not present]	Odds ratio: 1.760 (1.490-2.070) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Other	Level of hospital care [Tertiary hospital vs. Not tertiary hospital]	Odds ratio: 0.900 (0.770-1.060) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Patient characteristics	Ethnicity [Unknown vs. White]	Odds ratio: 0.740 (0.500-1.110) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Patient characteristics	Ethnicity [Mixed vs. White]	Odds ratio: 0.840 (0.690-1.030) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Patient characteristics	Ethnicity [Black vs. White]	Odds ratio: 1.230 (1.010-1.500) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Patient characteristics	Ethnicity [Asian vs. White]	Odds ratio: 0.830 (0.610-1.120) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Patient characteristics	Gender [Male vs. Female]	Odds ratio: 1.140 (0.970-1.330) ^§	Hirsch
COVID-19 (Acute Kidney Injury)	Patient characteristics	Age [1 year increase vs. Not applicable]	Odds ratio: 1.030 (1.030-1.040) ^§	Hirsch
COVID-19 (severe/critical)	Laboratory Findings	Cardiac troponin [missing vs. <0.1]	Odds ratio: 0.840 (0.510-1.400) ^§	Petrilli
COVID-19 (severe/critical)	Laboratory Findings	Cardiac troponin [>1 vs. <0.1]	Odds ratio: 4.780 (2.100-10.900) ^§	Petrilli
COVID-19 (severe/critical)	Laboratory Findings	Cardiac troponin [0.1-1 vs. <0.1]	Odds ratio: 2.090 (1.510-2.900) ^§	Petrilli
COVID-19 (severe/critical)	Laboratory Findings	Procalcitonin [missing vs. 0-0.5]	Odds ratio: 0.750 (0.440-1.300) ^§	Petrilli
COVID-19 (severe/critical)	Laboratory Findings	Procalcitonin [>0.5 vs. 0-0.5]	Odds ratio: 1.540 (1.180-2.000) ^§	Petrilli
COVID-19 (severe/critical)	Laboratory Findings	Serum ferritin [missing vs. 0-300]	Odds ratio: 0.750 (0.390-1.500) ^§	Petrilli
COVID-19 (severe/critical)	Laboratory Findings	Serum ferritin [>2500 vs. 0-300]	Odds ratio: 1.400 (0.940-2.100) ^§	Petrilli
COVID-19 (severe/critical)	Laboratory Findings	Serum ferritin [>1000-2500 vs. 0-300]	Odds ratio: 1.140 (0.830-1.600) ^§	Petrilli

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