COVID-19 Risk Factors
literature database & meta-analysis

Last update : 2020-08-04 16:24:58 (GMT+2)   |  276 factors investigated   |  1766 estimates included  |  219 articles processed  |  QC progress: 51%

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Green: significant protective factor
Red: significant risk factor
§ adjusted estimate (see article details)
estimated using data reported in the article
Outcome Risk category Risk [exposed vs. unexposed] Risk estimate (95% CI) Author [URL] View QC
COVID-19 (severe/fatal) Treatment Concomitant medication [Anti-tumor treatment <=14 days before COVID-19 diagnosis vs. Anti-tumor treatment >14 days before COVID-19 diagnosis] Hazard ratio: 4.080 (1.090-15.320) § Zhang
COVID-19 (severe/critical) Patient characteristics Gender [Male vs. Female] Odds ratio: 1.610 (1.250-2.070) Xu
COVID-19 (severe/critical) Patient characteristics Age [1 year increase vs. Not applicable] Weighted Mean Difference: 11.890 (8.630-15.140) § Xu
SARS COV-2 infection Patient characteristics Age [40-49 years vs. 20-39 years] Odds ratio: 1.010 (0.630-1.620) Russell
SARS COV-2 infection Patient characteristics Age [50-59 years vs. 20-39 years] Odds ratio: 2.000 (1.370-2.920) Russell
SARS COV-2 infection Patient characteristics Age [60-69 years vs. 20-39 years] Odds ratio: 2.730 (2.010-3.710) Russell
SARS COV-2 infection Patient characteristics Age [70-79 years vs. 20-39 years] Odds ratio: 3.450 (2.560-4.640) Russell
SARS COV-2 infection Patient characteristics Age [80-89 years vs. 20-39 years] Odds ratio: 3.830 (2.560-5.730) Russell
Developing COVID-19 after contamination Patient characteristics Age [40-49 years vs. 20-39 years] Odds ratio: 0.460 (0.160-1.330) Russell
Developing COVID-19 after contamination Patient characteristics Age [50-59 years vs. 20-39 years] Odds ratio: 0.170 (0.070-0.410) Russell
Developing COVID-19 after contamination Patient characteristics Age [60-69 years vs. 20-39 years] Odds ratio: 0.140 (0.070-0.300) Russell
Developing COVID-19 after contamination Patient characteristics Age [70-79 years vs. 20-39 years] Odds ratio: 0.130 (0.060-0.270) Russell
Developing COVID-19 after contamination Patient characteristics Age [80-89 years vs. 20-39 years] Odds ratio: 0.220 (0.090-0.530) Russell
COVID-19 (any condition) Patient characteristics Age [40-49 years vs. 20-39 years] Odds ratio: 0.840 (0.490-1.440) Russell
COVID-19 (any condition) Patient characteristics Age [50-59 years vs. 20-39 years] Odds ratio: 1.050 (0.650-1.690) Russell
COVID-19 (any condition) Patient characteristics Age [60-69 years vs. 20-39 years] Odds ratio: 1.250 (0.860-1.800) Russell
COVID-19 (any condition) Patient characteristics Age [70-79 years vs. 20-39 years] Odds ratio: 1.440 (1.010-2.040) Russell
COVID-19 (any condition) Patient characteristics Age [80-89 years vs. 20-39 years] Odds ratio: 2.160 (1.330-3.490) Russell
Asymptomatic SARS COV-2 Patient characteristics Age [40-49 years vs. 20-39 years] Odds ratio: 1.880 (0.730-4.800) Russell
Asymptomatic SARS COV-2 Patient characteristics Age [50-59 years vs. 20-39 years] Odds ratio: 6.460 (3.130-13.320) Russell
Asymptomatic SARS COV-2 Patient characteristics Age [60-69 years vs. 20-39 years] Odds ratio: 9.400 (4.870-18.140) Russell
Asymptomatic SARS COV-2 Patient characteristics Age [70-79 years vs. 20-39 years] Odds ratio: 12.140 (6.340-23.230) Russell
Asymptomatic SARS COV-2 Patient characteristics Age [80-89 years vs. 20-39 years] Odds ratio: 10.010 (4.730-21.200) Russell
COVID-19 (severe/fatal) Comorbidities Diabetes [Present vs. Not present] Hazard ratio: 2.340 (1.350-4.050) Wu
COVID-19 (severe/fatal) Laboratory Findings Neutrophils [Abnormal at admission vs. Normal] Hazard ratio: 1.140 (1.090-1.190) Wu
COVID-19 (severe/fatal) Laboratory Findings Lymphocytes [Abnormal at admission vs. Normal] Hazard ratio: 0.370 (0.210-0.630) Wu
COVID-19 (severe/fatal) Laboratory Findings CD3 [Abnormal at admission vs. Normal] Hazard ratio: 0.830 (0.720-0.960) Wu
COVID-19 (severe/fatal) Laboratory Findings CD4 [Abnormal at admission vs. Normal] Hazard ratio: 0.740 (0.590-0.930) Wu
COVID-19 (severe/fatal) Laboratory Findings CD8 [Abnormal at admission vs. Normal] Hazard ratio: 0.740 (0.530-1.040) Wu
COVID-19 (severe/fatal) Laboratory Findings Total bilirubin [Abnormal at admission vs. Normal] Hazard ratio: 1.050 (1.020-1.080) Wu
COVID-19 (severe/fatal) Laboratory Findings AST [Abnormal at admission vs. Normal] Hazard ratio: 1.020 (1.010-1.030) Wu
COVID-19 (severe/fatal) Laboratory Findings ALT [Abnormal at admission vs. Normal] Hazard ratio: 1.000 (0.999-1.010) Wu
COVID-19 (severe/fatal) Laboratory Findings Albumin [Abnormal at admission vs. Normal] Hazard ratio: 0.490 (0.370-0.660) Wu
COVID-19 (severe/fatal) Laboratory Findings Globulin [Abnormal at admission vs. Normal] Hazard ratio: 2.320 (1.450-3.710) Wu
COVID-19 (severe/fatal) Laboratory Findings Prealbumin [Abnormal at admission vs. Normal] Hazard ratio: 0.990 (0.980-0.990) Wu
COVID-19 (severe/fatal) Laboratory Findings Urea [Abnormal at admission vs. Normal] Hazard ratio: 1.130 (1.090-1.180) Wu
COVID-19 (severe/fatal) Laboratory Findings Creatinine [Abnormal at admission vs. Normal] Hazard ratio: 1.050 (1.010-1.100) Wu
COVID-19 (severe/fatal) Laboratory Findings Glucose [Abnormal at admission vs. Normal] Hazard ratio: 1.130 (1.080-1.190) Wu
COVID-19 (severe/fatal) Laboratory Findings CK-MB [Abnormal at admission vs. Normal] Hazard ratio: 1.010 (1.000-1.020) Wu
COVID-19 (severe/fatal) Laboratory Findings Cholinesterase [Abnormal at admission vs. Normal] Hazard ratio: 0.810 (0.730-0.900) Wu
COVID-19 (severe/fatal) Laboratory Findings Cystatin C [Abnormal at admission vs. Normal] Hazard ratio: 1.690 (1.310-2.190) Wu
COVID-19 (severe/fatal) Laboratory Findings LDH [Abnormal at admission vs. Normal] Hazard ratio: 1.610 (1.440-1.790) Wu
COVID-19 (severe/fatal) Laboratory Findings a-HBDH [Abnormal at admission vs. Normal] Hazard ratio: 1.740 (1.520-1.990) Wu
COVID-19 (severe/fatal) Laboratory Findings LDL [Abnormal at admission vs. Normal] Hazard ratio: 0.630 (0.440-0.880) Wu
COVID-19 (severe/fatal) Laboratory Findings hs-CRP [Abnormal at admission vs. Normal] Hazard ratio: 4.810 (1.520-15.270) Wu
COVID-19 (severe/fatal) Laboratory Findings IL-6 [Abnormal at admission vs. Normal] Hazard ratio: 1.020 (1.000-1.050) Wu
COVID-19 (severe/fatal) Laboratory Findings Serum ferritin [Abnormal at admission vs. Normal] Hazard ratio: 3.530 (1.520-8.160) Wu
COVID-19 (severe/fatal) Laboratory Findings PT [Abnormal at admission vs. Normal] Hazard ratio: 1.560 (1.320-1.830) Wu
COVID-19 (severe/fatal) Laboratory Findings APTT [Abnormal at admission vs. Normal] Hazard ratio: 0.970 (0.940-1.010) Wu
COVID-19 (severe/fatal) Laboratory Findings D-dimer [Abnormal at admission vs. Normal] Hazard ratio: 1.030 (1.010-1.040) Wu
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